Ivanenkov, Y.A.,
Yu. Filyaeva, K.,
Matniyazov, , R.T.,
Baymiev, A.K.,
Baymiev, A.K.,
Vladimirova, A.A.,
Yamidanov, R.S.,
Mavzyutov, A.R.,
Zileeva, Z.R.,
Zainullina, L.F.,
Vakhitova, J.V.,
Marina, V.I.,
Terentiev, V.A.,
Osterman, I.A.,
Kartsev, V.G.,
Bezrukov, D.S.,
Dontsova, O.A. (2021) compound exhibited an MIC of 13.
5 µM (6.25 µg/ml) and a relatively low cytotoxicity against HEK293 cells
, new less toxic ThS
inhibitors must be sought and created. The GUSAR 2013 program was used to study
, new less toxic ThS
inhibitors must be sought and created. The GUSAR 2013 program was used to study
and quinazolin-4-imine derivatives, well-known antifolate thymidylate synthase (TYMS)
inhibitors, has been