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HEMOSTATICAL ACTIVITY OF NEW BENZYLAMMONIUM SALT 2-[3 METHYL-1-N-PROPYL-7-(1,1-DIOXOTIETHANYL-3)XANTINYL-8-THIO]ACETIC ACID
Urakov, A.L., Samorodov, A.V., Kamilov, F.K., Khaliullin, F.A., Gubaeva, R.A. (2017)
activity of some new nitrogen-containing heterocyclic derivatives relating to hemostasis system in vitro
SYNTHESIS, ANTIDEPRESSANT ACTIVITY, AND PREDICTION OF TOXIC RISKS OF 3-ALKOXY(SULFANYL)THIETANE-1,1-DIOXIDES
KHALIULLIN, F.A., NIKITINA, I.L., KLEN, E., GAISINA, G.G., MAKAROVA, N.N. (2020)
FORCED-SWIM TEST
Синтез и антидепрессивная активность 4-алкил-5-бром-2,4-дигидро-2- (тиетан-3-YL) -1,2,4-триазол-3-онов
Synthesis and Antidepressant Activity of 4-Alkyl-5-Bromo-2,4-Dihydro-2-(Thietan-3-YL)-1,2,4-Triazol-3-Ones
Khaliullin, F.A., Nikitina, I.L., Klen, E.E., Miftakhova, A.F., Makarova, N.N., Gabidullin, R.A., Gilmanova, A.G., Халиуллин, Ф.А., Никитина, И.Л., Клен, Э., Мифтахова, А.Ф., Макарова, Н. Н., Габидуллин, Р.А., Гильманова, А.Г. (2021)
forced-swim test
THE OFF-LABEL USE OF DRUGS FOR PARENTERAL NUTRITION AS A SOLVENT OF SUBSTANCES SLIGHTLY SOLUBLE IN WATER IN PHARMACOLOGICAL RESEARCH
Urakov, A.L., Mustafin, I.G., Samorodov, A.V., Kamilov, F.K., Khaliullin, F.A. (2017)
is performed according to the “guidance on preclinical research of new pharmacological substances” in vitro
THROMBOELASTOGRAPHY AS AN INSTRUMENT OF PRECLINICAL STUDIES OF THE POTENTIAL DRUG
URAKOV, A.L., MUSTAFIN, I.G., NABIULLINA, R.M., BASHIROVA, L.I., MOCHALOV, K.S., SAMORODOV, A.V., KHALIULLIN, F.A., LIPATOV, D.O., KORUNAS, V.I., KHALIMOV, A.R. (2020)
activated TEG, in vitro hemostatic system hyperactivity modeling was carried out with the blood of healthy
SYNTHESIS AND BIOLOGICAL ACTIVITY OF 5-ALKOXY- AND 5-AMINO-SUBSTITUTED 3-BROMO-4-NITRO-1-(THIETAN-3-YL)-1H-PYRAZOLES
KHALIULLIN, F.A., KLEN, E.E., PAVLOV, V.N., SAMORODOV, A.V., SHEPILOVA, S.O., MAKAROVA, N.N., NURLANOVA, S.N., ABZALILOV, T.N. (2022)
. The structures of the synthesized compounds were established by IR, PMR, and 13C NMR spectroscopy. In vitro
SYNTHESIS AND ANTIDEPRESSANT PROPERTIES OF 2-[3-METHYL-7-(THIETANYL-3)-1-ETHYLXANTHINYL-8-THIO] ACETIC ACID HYDRAZIDES
Valeeva, L.A., Davlyatova, G.G., Shabalina, Yu.V., Isakova, A.V., Khaliullin, F.A., Nikitina, I.L. (2016)
-suspension tests (TST) and forced swimming tests (FST) found that 2-[3-methyl-7-(thietanyl-3)-1-ethylxanthinyl-8
СИНТЕЗ И БИОЛОГИЧЕСКАЯ АКТИВНОСТЬ ЭТИЛОВЫХ ЭФИРОВ 2-[8-АРИЛМЕТИЛИДЕНГИДРАЗИНО-3-МЕТИЛ-7-(1-ОКСОТИЕТАНИЛ-3)-КСАНТИНИЛ-1]УКСУСНЫХ КИСЛОТ
SYNTHESIS AND BIOLOGICAL ACTIVITY OF ETHYL 2-[8-ARYLMETHYLIDENEHYDRAZINO-3-METHYL-7-(1-OXOTHIETAN-3-YL)XANTH-1-YL]ACETATES
Гуревич, К.Г., Ураков, А.Л., Клен, Е.Э., Самородов, А.В., Никитина, И.Л., Халиуллин, Ф.А., Небогатова, В.А., Макарова, Н.Н., Шепилова, С.О., Баширова, Л.И., Халимов, А.Р., GUREVICH K.G., URAKOV A.L., BASHIROVA L.I., KLEN E.E., SAMORODOV A.V., NIKITINA I.L., KHALIULLIN F.A., NEBOGATOVA V.A., MAKAROVA N.N., SHEPILOVA S.O., KHALIMOV A.R. (2020)
активность оценивалась in vitro и на лабораторных животных для выявления перспективных соединений
СИНТЕЗ И БИОЛОГИЧЕСКАЯ АКТИВНОСТЬ ЭТИЛОВЫХ ЭФИРОВ 2-[8-АРИЛМЕТИЛИДЕНГИДРАЗИНО-3-МЕТИЛ-7-(1-ОКСОТИЕТАНИЛ-3)-КСАНТИНИЛ-1]УКСУСНЫХ КИСЛОТ
SYNTHESIS AND BIOLOGICAL ACTIVITY OF ETHYL 2-[8-ARYLMETHYLIDENEHYDRAZINO-3-METHYL-7-(1-OXOTHIETAN-3-YL)XANTH-1-YL]ACETATES
ГУРЕВИЧ, К.Г., УРАКОВ, А.Л., КЛЕН, Е.Э., САМОРОДОВ, А.В., НИКИТИНА, И.Л., ХАЛИУЛЛИН, Ф.А., НЕБОГАТОВА, В.А., МАКАРОВА, Н.Н., ШЕПИЛОВА, С.О., БАШИРОВА, Л.И., ХАЛИМОВ, А.Р, Gurevich K.G., Urakov A.L., Bashirova L.I., Klen E.E., Samorodov A.V., Nikitina I.L., Khaliullin F.A., Nebogatova V.A., Makarova N.N., Shepilova S.O., Khalimov A.R. (2020)
помощью ИК-, ЯМР спектроскопии и элементного анализа. Исследования in vitro и на лабораторных животных для
3-SUBSTITUTED THIETANE-1,1-DIOXIDES: SYNTHESIS, ANTIDEPRESSANT ACTIVITY, AND IN SILICO PREDICTION OF THEIR PHARMACOKINETIC AND TOXICOLOGICAL PROPERTIES
Klen, E.E, Nikitina, I.L., Makarova, N.N, Miftakhova, A.F, Ivanova, O.A, Khaliullin, F.A., Alekhin, E.K. (2017)
-suspension (TST) and forced-swim tests (FST) that were comparable with those of imipramine. Low toxicity risks

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