IVABRADINE PREVENTS HEART RATE ACCELERATION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND CORONARY HEART DISEASE AFTER SALBUTAMOL INHALATION). Cross-over, randomized, open label study design. 20 patients (18 males and two females) with COPD stage

males). In the treatment group (23 patients), after professional oral hygiene and correction of hygiene

model after peroral administration to male Wistar rats. It was found that GA and its conjugate IV at a

: The study included 80 male white rats. All the animals were divided into 2 groups. A model of systemic

and fluoxetine) were administered once intraperitoneally to outbred male mice 4 h (Experiment 1) and 18 h

(BMA). The model of anaerobic physical exercise was forced swimming of male rats with a load of 10

administration to male mice. The most significant effects were typical of 5-piperazinopyrazoles IIh and IIg

.26), with adjusting for older age (OR: 1.08), male sex (OR: 4.18), higher waist-hip ratio (OR: 5.53), current smoking