-substituted thietane-1,1-dioxide derivative (N-199/1) exhibiting
antidepressant properties, in several tests
Khaliullin, F. A.,
Klen, E. E.,
Nikitina, I. L.,
Pavlov, V. N.,
Rozit, G. A.,
Gaisina, G. G.,
Samorodov, A. V. (2023) . An in vivo
study of the
antidepressant activity revealed the promising compound 1-(1,1-dioxidothietan-3-yl)-4
Klen, E.E,
Nikitina, I.L.,
Makarova, N.N,
Miftakhova, A.F,
Ivanova, O.A,
Khaliullin, F.A.,
Alekhin, E.K. (2017) -substituted thietane-1,1-dioxide IId (2 and 20 mg/kg) displayed
antidepressant properties in tail
significant
antidepressant properties when administered intraperitoneally (i.p.) to mice once or repeatedly
A compound with low toxicity and pronounced
antidepressant activity upon single and long