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СПОСОБ СОВМЕСТНОГО ПОЛУЧЕНИЯ 3'-ЗАМЕЩЕННЫХ СПИРО[3,9-ДИОКСАТЕТРАЦИКЛО[5.3.2.02,4.08,10]ДОДЕЦ-5-ЕН-11,2'-ОКСИРАНОВ] И СПИРО[3,9-ДИОКСАТЕТРАЦИКЛО[5.3.2.02,4.08,10]ДОДЕЦ-5-ЕН-12,2'-ОКСИРАНОВ], ПРОЯВЛЯЮЩИХ ПРОТИВООПУХОЛЕВУЮ АКТИВНОСТЬMETHOD FOR COMBINED PRODUCTION OF 3'-SUBSTITUTED SPIRO[3,9-DIOXATETRACYCLO[5_3_2_02,4_08,10]DODEC-5

ФЕНОЛЬНЫЕ СОЕДИНЕНИЯ ИЗ JUNIPERUS COMMUNIS L. VAR. SAXATILISPHENOL COMPOUNDS FROM JUNIPERUS COMMUNIS L. VAR. SAXATILIS

compounds; they are discussed in the framework of modern pharmacognostic analysis. Data on chemical

synthesized by reaction of III with organic and inorganic bases. Compounds possessing antiaggregant activity

and amides derived from commercial aryloxyacetyl chlorides were synthesized. The structures of the compounds

-butyl-3-methylxanthines in 85 – 98% yields. The structures of the compounds were confirmed by IR and PMR

]- acetate salts containing thietanyl and dioxothietanyl rings. The structures of the synthesized compounds

]- acetate salts containing thietanyl and dioxothietanyl rings. The structures of the synthesized compounds

compound with high anti-inflammatory activity in carrageenan- and formalin-induced mouse inflammation

-(1,1-dioxothietanyl- 3)-1,2,4-triazole with sodium alkoxides and thioalkoxides. Compounds IIa (2 mg/kg) and IIh (6 mg

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