SYNTHESIS AND ANTI-AGGREGATION ACTIVITY OF 2-[3-METHYL-1-ETHYLXANTH-8-YLTHIO]ACETATE SALTS CONTAINING THIETANYL AND DIOXOTHIETANYL RINGS

GUREVICH, K.G.; URAKOV, A.L.; KHALIULLIN, F.A.; SAMORODOV, A.V.; SHABALINA, Y.V.; KAMILOV, F.KH.; MURATAEV, D.Z.; BASHIROVA, L.I.

SYNTHESIS AND ANTI-AGGREGATION ACTIVITY OF 2-[3-METHYL-1-ETHYLXANTH-8-YLTHIO]ACETATE SALTS CONTAINING THIETANYL AND DIOXOTHIETANYL RINGS

GUREVICH, K.G., URAKOV, A.L., KHALIULLIN, F.A., SAMORODOV, A.V., SHABALINA, Y.V., KAMILOV, F.KH., MURATAEV, D.Z., BASHIROVA, L.I.

Publication date: 2020

DOI: 10.1007/s11094-020-02220-z

Abstract:

Reactions of 2-[1-ethyl-3-methyl-7-(thietan-3-yl)- and 2-[1-ethyl-3-methyl-7-(1,1-dioxothietan-3-yl)xanth- 8-ylthio]acetic acids with amines (diethylamine, monoethanolamine, diethanolamine, triethanolamine, piperidine, cyclohexylamine, and benzylamine) gave 42 – 89% yields of 2-[1-ethyl-3-methyl-xanth-8-ylthio]- acetate salts containing thietanyl and dioxothietanyl rings. The structures of the synthesized compounds were confirmed using IR and PMR spectroscopy. The synthesized compounds exhibited anti-aggregation activity. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.

Keywords:
ANTI-AGGREGATION ACTIVITY, THIETANES, XANTHINES, Scopus, Web of Science

Издатель: Springer New York Consultants Bureau

Тип: Article

SYNTHESIS AND ANTI-AGGREGATION ACTIVITY OF 2-[3-METHYL-1-ETHYLXANTH-8-YLTHIO]ACETATE SALTS CONTAINING THIETANYL AND DIOXOTHIETANYL RINGS

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