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SYNTHESIS AND ANTIDEPRESSANT ACTIVITY OF 8-AMINO-SUBSTITUTED 1-BUTYL-3-METHYLXANTHINES CONTAINING A THIETANE RING
SHABALINA, Y.V., KHALIULLIN, F.A., NIKITINA, I.L., MIFTAKHOVA, A.F.., SHARAFUTDINOV, R.M (2020)
spectroscopy. The synthesized compounds exhibited antidepressant activity.
Synthesis and Antidepressant Properties of 3-Methyl-7-(1,1-Dioxothietan-3-YL)-8-Cyclohexylamino-1-Ethyl-1H-Purine-2,6(3H,7H)-Dione
Khaliullin, F.A., Shabalina, Y.V., Davlyatova, G.G., Valeeva, L.A. (2018)
)-dione and cyclohexylamine and exhibited antidepressant activity that was most pronounced at a dose of 1.6 mg/kg.
SYNTHESIS AND ANTIDEPRESSANT PROPERTIES OF 3-METHYL-7-(1,1-DIOXOTHIETAN-3-YL)-8-CYCLOHEXYLAMINO-1-ETHYL-1H-PURINE-2,6(3H,7H)-DIONE
Khaliullin, F.A., Shabalina, Y.V., Davlyatova, G.G., Valeeva, L.A. (2018)
)-dione and cyclohexylamine and exhibited antidepressant activity that was most pronounced at a dose of 1.6 mg/kg. © 2018
Synthesis and Antidepressant Activity of Thietane-Containing 4-(2-oxo-2-phenylethyl)-1H-1,2,4-triazol-4-ium Bromides
Khaliullin, F.A., Klen, E.E., Nikitina, I.L., Pavlov, V.N., Rozit, G.A., Gaisina, G.G., Samorodov, A.V. (2023)
. An in vivo study of the antidepressant activity revealed the promising compound 1-(1,1-dioxidothietan-3-yl)-4
Synthesis and Evaluation of the Antidepressant Activity of 5-Amine-Substituted 3-Bromo-1-(Thietan-3-yl)-4-Nitro-1H-Pyrazoles
Klen, E.E., Nikitina, I.L., Khaliullin, F.A., Shepilova, S.O., Nikitina, E.A., Gaisina, G.G., Samorodov, A.V., Pavlov, V.N. (2024)
bioavailability. The compounds exhibited varying degrees of antidepressant activity after a single intraperitoneal
Synthesis and Antidepressant Activity of Thietane-Containing 4-(2-oxo-2-phenylethyl)-1H-1,2,4-triazol-4-ium Bromides
Khaliullin, F. A., Klen, E. E., Nikitina, I. L., Pavlov, V. N., Rozit, G. A., Gaisina, G. G., Samorodov, A. V. (2023)
. An in vivo study of the antidepressant activity revealed the promising compound 1-(1,1-dioxidothietan-3-yl)-4
SYNTHESIS AND ANTIDEPRESSANT PROPERTIES OF 2-[3-METHYL-7-(THIETANYL-3)-1-ETHYLXANTHINYL-8-THIO] ACETIC ACID HYDRAZIDES
Valeeva, L.A., Davlyatova, G.G., Shabalina, Yu.V., Isakova, A.V., Khaliullin, F.A., Nikitina, I.L. (2016)
-thio]acetic acid hydrazide exhibited antidepressant activity that was most pronounced at a dose of 12
SYNTHESIS, ANTIDEPRESSANT ACTIVITY, AND PREDICTION OF TOXIC RISKS OF 3-ALKOXY(SULFANYL)THIETANE-1,1-DIOXIDES
KHALIULLIN, F.A., NIKITINA, I.L., KLEN, E., GAISINA, G.G., MAKAROVA, N.N. (2020)
/kg) exhibited antidepressant-like effects at doses equimolar to amitriptyline (10 mg/kg); IId (2 mg/kg) and IIb
АНТИДЕПРЕССИВНЫЕ СВОЙСТВА НОВЫХ ПРОИЗВОДНЫХ ДИГИДРОТИАЗОЛОКСАНТИНОВ И ПРОГНОЗ ПАРАМЕТРОВ ИХ ОСТРОЙ ТОКСИЧНОСТИ in silico
ANTIDEPRESSANT PROPERTIES OF NEW DIHYDROTHIAZOLOXANTHINE DERIVATIVES AND PREDICTION OF THEIR ACUTE TOXICITY PARAMETERS in silico
Исламова, Э.Э., Смирнов, И.А., Никитина, Е.А., Желнина, А.Д., Казачков, М.М, Islamova, E.E., Smirnov, I.A., Nikitina, E.A., Zhelnina, A.D., Kazachkov, M.M. (2024)
ANTIDEPRESSANT PROPERTIES OF NEW DIHYDROTHIAZOLOXANTHINE DERIVATIVES AND PREDICTION OF THEIR ACUTE
3-SUBSTITUTED THIETANE-1,1-DIOXIDES: SYNTHESIS, ANTIDEPRESSANT ACTIVITY, AND IN SILICO PREDICTION OF THEIR PHARMACOKINETIC AND TOXICOLOGICAL PROPERTIES
Klen, E.E, Nikitina, I.L., Makarova, N.N, Miftakhova, A.F, Ivanova, O.A, Khaliullin, F.A., Alekhin, E.K. (2017)
-substituted thietane-1,1-dioxide IId (2 and 20 mg/kg) displayed antidepressant properties in tail

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