of evidence strongly suggests that miRNAs serve as crucial regulators, actively shaping both the physiological

-penetrating peptides, nanoparticles and other biologically active agents. In this review we will focus on the recent

. It can modulate the activity of interleukin-1 receptor-associated kinase, IRAK1, IRAK2 adaptor proteins

, activation of signaling pathways, and cytokine production, which are all crucial for deploying appropriate

for influencing the inflammatory cascade in intervertebral discs mediated by abnormal activation of inflammasomes

both changes in residual glucose level in the nutrient medium, without active participation of glucose