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Preparation of an Adduct of Levoglucosenone and Resorcinol and its in vitro Antiplatelet and Anticoagulant Activity
Faizullina, L.K., Khalilova, Y.А., Valeev, F.А., Pavlov, V.N., Samorodov, A.V. (2021)
-crown-6 ether in toluene. In vitro anticoagulant and antiplatelet activity of the adduct was studied
SYNTHESIS AND BIOLOGICAL ACTIVITY OF 5-ALKOXY- AND 5-AMINO-SUBSTITUTED 3-BROMO-4-NITRO-1-(THIETAN-3-YL)-1H-PYRAZOLES
KHALIULLIN, F.A., KLEN, E.E., PAVLOV, V.N., SAMORODOV, A.V., SHEPILOVA, S.O., MAKAROVA, N.N., NURLANOVA, S.N., ABZALILOV, T.N. (2022)
studies of the antiplatelet, anticoagulant, and antioxidant activity revealed promising compounds
SYNTHESIS AND ANTIAGGREGANT AND ANTICOAGULANT ACTIVITY OF AMINO-ACID SALTS AND COMPUTER SIMULATION OF THE INTERACTION OF THEIR STRUCTURES WITH THE SURFACE OF CYCLOOXYGENASE
Gurevich, K.G., Urakov, A.L., Purygin, P.P., Abzalilov, T.A., Garaev, T.M., Zarubin, Y.P., Afanasiev, V.A., Sakaev, V.E., Samoredov, A.V., Pavlov, V.N., Lovtsova, L.V. (2023)
Effective drugs with antiaggregant and anticoagulant activity are known to possess side effects
Synthesis and Antidepressant Activity of Thietane-Containing 4-(2-oxo-2-phenylethyl)-1H-1,2,4-triazol-4-ium Bromides
Khaliullin, F.A., Klen, E.E., Nikitina, I.L., Pavlov, V.N., Rozit, G.A., Gaisina, G.G., Samorodov, A.V. (2023)
. An in vivo study of the antidepressant activity revealed the promising compound 1-(1,1-dioxidothietan-3-yl)-4
Synthesis and Evaluation of the Antidepressant Activity of 5-Amine-Substituted 3-Bromo-1-(Thietan-3-yl)-4-Nitro-1H-Pyrazoles
Klen, E.E., Nikitina, I.L., Khaliullin, F.A., Shepilova, S.O., Nikitina, E.A., Gaisina, G.G., Samorodov, A.V., Pavlov, V.N. (2024)
bioavailability. The compounds exhibited varying degrees of antidepressant activity after a single intraperitoneal
Synthesis and Antidepressant Activity of Thietane-Containing 4-(2-oxo-2-phenylethyl)-1H-1,2,4-triazol-4-ium Bromides
Khaliullin, F. A., Klen, E. E., Nikitina, I. L., Pavlov, V. N., Rozit, G. A., Gaisina, G. G., Samorodov, A. V. (2023)
. An in vivo study of the antidepressant activity revealed the promising compound 1-(1,1-dioxidothietan-3-yl)-4
Myeloid differential protein-2 inhibition improves diabetic cardiomyopathy via p38MAPK inhibition and AMPK pathway activation
Qian, J., Zhuang, F., Chen, Y., Fan, X., Wang, J., Wang, Z., Wang, Y., Xu, M., Samorodov, A.V., Pavlov, V.N., Liang, G. (2022)
under high glucose condition, which was mediated by p38MAPK activation. MD2 knockout or pharmacological
СРЕДСТВО С АНТИАГРЕГАЦИОННОЙ АКТИВНОСТЬЮ И СПОСОБ ЕГО ПОЛУЧЕНИЯ
AGENT WITH ANTIAGGREGATORY ACTIVITY AND METHOD FOR PRODUCTION THEREOF
ПАВЛОВ, В.Н., ПУРЫГИН, П.П., ЗАРУБИН, Ю.П., АБЗАЛИЛОВ, Т.А., ХАЙРЗАМАНОВА, К.А., МОЧАЛОВ, К.С., ФАХРЕТДИНОВА, А.К., МУМИНОВ, Д.Д., КЛИМОВИЧ, А.К., САМОРОДОВ, А.В., PAVLOV, V.N., PURYGIN, P.P., ZARUBIN, Y.P., ABZALILOV, T.A., KHAJRZAMANOVA, K.A., MOCHALOV, K.S., FAKHRETDINOVA, A.K., MUMINOV, D.D., KLIMOVICH, A.K., SAMORODOV, A.V. (2022)
AGENT WITH ANTIAGGREGATORY ACTIVITY AND METHOD FOR PRODUCTION THEREOF
Cardamonin inhibits LPS-induced inflammatory responses and prevents acute lung injury by targeting myeloid differentiation factor 2
Yang, L., Luo, W., Zhang, Q, Hong, S., Wang, Y., Samorodov, A.V., Chattipakorn, N., Pavlov, V.N., Liang, G. (2021)
compounds were screened for their anti-inflammatory activity in LPS-stimulated macrophages. PCR array, SPR
Curcumin analogue C66 attenuates obesity-induced myocardial injury by inhibiting JNK-mediated inflammation
Ye, L., Chen, X., Wang, M., Jin, L., Zhuang, Z., Yang, D., Guan, X., Samorodov, A.V., Pavlov, V.N., Chattipakorn, N., Feng, J., Wang, Y., Luo, W., Liang, G. (2021)
administration attenuates HFD-induced myocardial inflammation by inhibiting NF-κB and JNK activation in mouse

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