Статья
SYNTHESIS, ISOMERISM, AND HYPOTENSIVE ACTIVITY OF THIETHANE-CONTAINING HYDRAZONES OF URACILYLACETIC ACID
2014
By the reaction of 2-[6-methyl-1-(thiethane-3-yl)uracil-3-yl]acetic acid hydrazide with aryl aldehydes and acetophenone derivatives, acylhydrazones have been obtained, which exist in DMSO solutions as a mixture of two stereoisomers of an EC=N-isomer, due to the hindered internal rotation around the hydrazide bond. It has been found that the compounds synthesized exhibit a hypotensive activity. © 2014 Pleiades Publishing, Ltd.
Meshcheryakova, S.A., Kataev, V.A., Nikolaeva, K.V., Perfilova, V.N., Borodin, D.D., Tyurenkov, I.N. SYNTHESIS, ISOMERISM, AND HYPOTENSIVE ACTIVITY OF THIETHANE-CONTAINING HYDRAZONES OF URACILYLACETIC ACID. 2014;
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