RT - Article
SR - Electronic
T1 - SYNTHESIS, ISOMERISM, AND HYPOTENSIVE ACTIVITY OF THIETHANE-CONTAINING HYDRAZONES OF URACILYLACETIC ACID
SP - 2018-10-03
A1 - Meshcheryakova, S.A., 
A1 - Kataev, V.A., 
A1 - Nikolaeva, K.V., 
A1 - Perfilova, V.N., 
A1 - Borodin, D.D., 
A1 - Tyurenkov, I.N., 
YR - 2014
UL - https://repo.bashgmu.ru/publication/645
AB - By the reaction of 2-[6-methyl-1-(thiethane-3-yl)uracil-3-yl]acetic acid hydrazide with aryl aldehydes and acetophenone derivatives, acylhydrazones have been obtained, which exist in DMSO solutions as a mixture of two stereoisomers of an EC=N-isomer, due to the hindered internal rotation around the hydrazide bond. It has been found that the compounds synthesized exhibit a hypotensive activity. © 2014 Pleiades Publishing, Ltd.