PT - JOURNAL ARTICLE
AU - Meshcheryakova, S.A., 
AU - Kataev, V.A., 
AU - Nikolaeva, K.V., 
AU - Perfilova, V.N., 
AU - Borodin, D.D., 
AU - Tyurenkov, I.N., 
TI - SYNTHESIS, ISOMERISM, AND HYPOTENSIVE ACTIVITY OF THIETHANE-CONTAINING HYDRAZONES OF URACILYLACETIC ACID
DP - 2018-10-03
SO - https://repo.bashgmu.ru/publication/645
AB - By the reaction of 2-[6-methyl-1-(thiethane-3-yl)uracil-3-yl]acetic acid hydrazide with aryl aldehydes and acetophenone derivatives, acylhydrazones have been obtained, which exist in DMSO solutions as a mixture of two stereoisomers of an EC=N-isomer, due to the hindered internal rotation around the hydrazide bond. It has been found that the compounds synthesized exhibit a hypotensive activity. © 2014 Pleiades Publishing, Ltd.