receiving antidepressant therapy, there is an urgent need for developing novel agents with antidepressant

significant antidepressant properties when administered intraperitoneally (i.p.) to mice once or repeatedly

Коррекция депрессивноподобного состояния у крыс, вызванного социальным стрессом, с помощью нового производного тиетан-1,1-диоксидаantidepressive agents

in the antidepressant effect of a new 3-substituted thietane-1,1-dioxide derivative (N-199/1) using tests with several

)-dione and cyclohexylamine and exhibited antidepressant activity that was most pronounced at a dose of 1.6 mg/kg.

spectroscopy. The synthesized compounds exhibited antidepressant activity.

-thio]acetic acid hydrazide exhibited antidepressant activity that was most pronounced at a dose of 12

SYNTHESIS AND ANTIDEPRESSANT PROPERTIES OF 3-METHYL-7-(1,1-DIOXOTHIETAN-3-YL)-8-CYCLOHEXYLAMINO-1-ETHYL-1H-PURINE-2,6(3H,7H)-DIONE)-dione and cyclohexylamine and exhibited antidepressant activity that was most pronounced at a dose of 1.6 mg/kg. © 2018

/kg) exhibited antidepressant-like effects at doses equimolar to amitriptyline (10 mg/kg); IId (2 mg/kg) and IIb

. An in vivo study of the antidepressant activity revealed the promising compound 1-(1,1-dioxidothietan-3-yl)-4