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on exosomal miRNAs analysis. © 2022 The Authors

. Modern studies demonstrate the high potential of exosomal miRNAs as diagnostic and prognostic markers

functional proteins. They can be small, about 20 nucleotides in length, and are known as microRNAs (miRNAs

that exosomal miRNAs are key modulators of tumour signaling and determinants of the tumour microenvironment

of the following exosomal microRNAs: miR-20a, miR-135a, miR-34b, miR-449c, miR-449c and control miR-16

Introduction Exosomal microRNAs (miRNAs) play an essential role in near and distant intercellular

and therapeutic targets. Exosomal ncRNAs are small RNA molecules that are secreted by cells and transported

, including rapid proliferative activity and invasion of neighboring tissues. MicroRNAs (miRNAs) are short

and organs. The content of exosomes depends on the cell type and includes mRNA, non-coding RNAs, DNA, and so

pathogenesis of HFRS is required. Determination of the expression level of exosomal microRNAs (miRNAs

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