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Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation
Zhang, Lu, Wang, Yi-ning, Ju, Jia-ming, Shabanova, Azaliia, Li, Yue, Fang, Ruo-nan, Sun, Jia-bin, Guo, Ying-ying, Jin, Tong-zhu, Liu, Yan-yan, Li, Tian-yu, Shan, Hong-li, Liang, Hai-hai, Yang, Bao-feng (2020)
/Bcl-2 and cytochrome c and improved mitochondrial function in MI mice via activating the AMPK-PGC1α
Metformin ameliorates cardiac conduction delay by regulating microRNA-1 in mice
LV, L., ZHANG, L., LI, R., LI, Y., YANG, R., LI, C., FANG, R., SHABANOVA, A., LI, X., LIU, Y., LIANG, H., ZHOU, Y., SHAN, H., ZHENG, N. (2020)
) mouse models were used. Mice were administered with Met in an intragastric manner. We found
Kaempferol attenuates streptozotocin-induced diabetic nephropathy by downregulating TRAF6 expression: The role of TRAF6 in diabetic nephropathy
Luo, W., Chen, X., Ye, L., Chen, X., Jia, W., Zhao, Y., Samorodov, A.V., Zhang, Y., Hu, X., Zhuang, F., Qian, J., Zheng, C., Liang, G., Wang, Y. (2021)
by regulating TRAF6 in DN. Material and methods: C57BL/6 mice were injected with streptozotocin to induce type 1
Myeloid differential protein-2 inhibition improves diabetic cardiomyopathy via p38MAPK inhibition and AMPK pathway activation
Qian, J., Zhuang, F., Chen, Y., Fan, X., Wang, J., Wang, Z., Wang, Y., Xu, M., Samorodov, A.V., Pavlov, V.N., Liang, G. (2022)
in DCM and to test the therapeutic effects of MD2 inhibitor C30 on DCM. Streptozotocin (STZ) was used
ANTIHYPOXIC ACTIVITY OF SEVERAL SCAFFOLD DERIVATIVES OF QUINOPIMARIC ACID
Vafina, G.F., Uzbekov, A.R., Gabdrakhmanova, S.F., Makara, N.S., Zarudii, F.S., Galin, F.Z. (2016)
. It was shown that compounds 3, 5, and 8 increased the lifespan of mice in various hypoxia models.
SYNTHESIS AND ANTIDEPRESSANT PROPERTIES OF 2-[3-METHYL-7-(THIETANYL-3)-1-ETHYLXANTHINYL-8-THIO] ACETIC ACID HYDRAZIDES
Valeeva, L.A., Davlyatova, G.G., Shabalina, Yu.V., Isakova, A.V., Khaliullin, F.A., Nikitina, I.L. (2016)
spectroscopic data. The acute toxicity was studied. The LD50 values were 700 mg/kg for outbred albino mice. Tail
NEUROPHARMACOLOGICAL ANALYSIS OF THE ANTIDEPRESSANT ACTION OF 2-[3-METHYL-7-(THIETAN-3-YL)-1-ETHYLXANTH-8-YLTHIO] ACETIC ACID HYDRAZIDE
VALEEVA, L.A., DAVLYATOVA, G.G ., SHIMANOVSKII, N.L. (2020)
action on GABA-ergic neurotransmission in brains of outbred white mice. M-20 at a dose of 12 mg
EFFECTS OF NOVEL HEXAHYDROPYRIMIDINE DERIVATIVES AS POTENTIAL LIGANDS OF M1 MUSCARINIC ACETYLCHOLINE RECEPTOR ON COGNITIVE FUNCTION, HYPOXIA-INDUCED LETHALITY, AND OXIDATIVE STRESS IN RODENTS
SAPOZHNIKOVA, T.A., BORISEVICH, S.S., KIREEVA, D.R., GABDRAKHMANOVA, S.F., KHISAMUTDINOVA, R.Y., MAKARA, N.S., GIBADULLINA, N.N., KHURSAN, S.L., ZARUDII, F.S. (2019)
the life span of mice undernormobaric hypoxia by 30% (P < 0.05) and, after injection of sodium
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1
Han, Z.B., Wang, X.X., Xu, Z.H., Cao, Y., Gong, R, Zagidullin, N., Sukhareva, N., Zhang, Y. (2021)
knockout mice exhibited decreased cardiac regenerative ability and heart function after neonatal apex
Cardamonin inhibits LPS-induced inflammatory responses and prevents acute lung injury by targeting myeloid differentiation factor 2
Yang, L., Luo, W., Zhang, Q, Hong, S., Wang, Y., Samorodov, A.V., Chattipakorn, N., Pavlov, V.N., Liang, G. (2021)
). The pharmacological effect of CAR was further evaluated in both LPS-stimulated macrophages and ALI mice model. Results

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