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–67 years from the Volga-Ural region. The DNA samples for the study were collected from 2000 to 2021

ЭПИГЕНЕТИЧЕСКАЯ МОДУЛЯЦИЯ В МЕДИЦИНЕ: РЕГУЛЯЦИЯ ГЕННОЙ ЭКСПРЕССИИ В КОНТЕКСТЕ ПАТОГЕНЕЗА И ТЕРАПИИ

such as proteins, lipids, RNA and DNA. Several studies have shown that their contents, including proteins

. These processes can increase the amount of DNA damage and lead to loss of control over cell division. A number

and organs. The content of exosomes depends on the cell type and includes mRNA, non-coding RNAs, DNA, and so

, including during aging. TEs’ expression is also regulated by epigenetic factors (DNA methylation, histone

. The purpose of this work was to investigate the DNA methylation level of miR-152 in 25 paired tissue samples

. The samples for the study were the DNA of 374 patients with GC and 365 healthy donors of various ethnicities

ПОИСК ИЗМЕНЕНИЙ НУКЛЕОТИДНОЙ ПОСЛЕДОВАТЕЛЬНОСТИ ГЕНА РЕМОДЕЛИРОВАНИЯ ХРОМАТИНА PBRM1 У ПАЦИЕНТОВ СО СВЕТЛОКЛЕТОЧНЫМ РАКОМ ПОЧКИ of the PBRM1 tumor suppressor gene in patients with ccRCC. 210 pairs of DNA samples isolated from ccRCC tissue

of Bashkortostan, sequencing the NF1 gene in their DNA samples as well as whole genome sequencing using the WGS

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