Роль мутаций в гене NF1 в спорадическом канцерогенезе for targeted therapy of both neurofibromatosis type 1 and sporadic neoplasms with mutations of this gene

, and FGFRL1 genes to examine the association between miRNA target site alteration and the incidence of OA

was experimentally validated as a direct target gene for miR-499a. Overexpression of PTEN was able to induce

basis for a specific targeted effect on reversible epigenetic mechanisms of their origin. Non

For several decades, research in tumor biology has focused on the involvement of genes encoding a

of regulatory sequences at the genomic level and interaction between microRNAs and the messenger RNAs of target

by the modifications of cell cycle-related genes or regulation of growth-related signals. Additionally, non

. Bioinformatic analyses were performed to identify a gene target, and CGGA and TCGA databases were checked

-22 nucleotides that regulate gene expression at the post-transcriptional level through interaction with 3