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dominant model), GRIA1 (rs2195450) (P = 0.015, OR = 1.35 in a dominant model), GRIN1 (rs6293) (P = 0

ASSOCIATIONS OF THE NRF2/KEAP1 PATHWAY AND ANTIOXIDANT DEFENSE GENE POLYMORPHISMS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE population). Logistic regression was used to detect the association of SNPs in different models. Linear

). Logistic regression was used to detect the association of SNPs in different models. Linear regression

, Russia). Logistic regression was used to detect the association of SNPs in different models. Linear

controls. Significant associations with COPD in the study group under an additive genetic model were

models. Linear regression analyses were performed to estimate the relationship between SNPs and lung

shown to be associated with obesity risk following an additive model, while the MC4R rs12970134 (p = 0

.72) polymorphisms were associated with COPD development in the recessive model. The nondeletion variant of CYP2A6

prognostic model was constructed based on the multiple regression and ROC analyses. The model included

prognostic model was constructed based on the multiple regression and ROC analyses. The model included

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