Статья
SYNTHESIS OF PYRINIDINE-2,4(1H,3H)-DIONE DERIVATIVES CONTAINING N-ALKYL SUBSTITUENTS
2017
Abstract—6-Methyluracil derivatives containing a gem-dichlorocyclopropane and a 1,3-dioxolane fragments were synthesized for the first time. The condensation of 6-methyluracil with chloromethyl derivatives gives a mixture of N1 - and N3 -monosubstituted products, and the profound N-alkylation of this compound provides disubstituted uracils. The structure of the synthesized compounds was studied by H1 and 13С NMR spectroscopy and their relative antioxidant activity was evaluated by luminol-dependent chemiluminescence measurements.
Раскильдина, Г.З., Валиев, В.Ф., Озден, И.В., Мещерякова, С.А., Спирихин, Л.В., Злоцкий, С.С., , , , , , . 2017;
Цитирование
