Статья

Focal therapy for localized prostate cancer: not all that glitters is gold

Antonio Franco, Jean de la Rosette, Cosimo De Nunzio
2026

In past years we are experiencing a shift toward earlier diagnosis of prostate cancer (PCa). The driving dynamics behind that are twofold. On one hand there is a greater public awareness in parallel to advancing professional insights, leading to the adoption of (in)formal screening strategies. Hence, numerous improved non-invasive enhanced diagnostic imaging modalities have become available. Traditionally the detection of PCa has been fuelled by prostatespecific antigen (PSA) and image-guided prostate tissue sampling. A proactive attitude towards decreasing the threshold of performing diagnostic investigations has led to an increase in making the (early) diagnosis of PCa. Consequently, this has led to an increase in the number of patients presenting with clinically organ-confined PCa.

Antonio Franco, Jean de la Rosette, Cosimo De Nunzio Focal therapy for localized prostate cancer: not all that glitters is gold. PROSTATE CANCER AND PROSTATIC DISEASES. 2026;29(2):461-463. https://doi.org/https:// doi.org/10.1038/s41391-026-01136-1
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