A series of 3-alkyloxy(sulfanyl)
thietane-
1,1-
dioxides were synthesized by reacting 3,5-dibromo-
1-(1,1Klen, E.E,
Nikitina, I.L.,
Makarova, N.N,
Miftakhova, A.F,
Ivanova, O.A,
Khaliullin, F.A.,
Alekhin, E.K. (2017) -substituted
thietane-
1,1-
dioxide IId (2 and 20 mg/kg) displayed antidepressant properties in tail
in the antidepressant effect of a new 3-substituted
thietane-
1,1-
dioxide derivative (N-199/
1) using tests with several
action and a fundamentally new mechanism of action. 3-ethoxythietane-
1,1-
dioxide (N-199/
1) is a new
-substituted
thietane-
1,1-
dioxide derivative (N-199/
1) exhibiting antidepressant properties, in several tests
Introduction: 3-ethoxythietane-
1,1-
dioxide (3ETD) is a novel molecule that has demonstrated
ИССЛЕДОВАНИЕ ДИАПАЗОНА ЭФФЕКТИВНЫХ ДОЗ НОВОГО ПРОИЗВОДНОГО 3-ЗАМЕЩЕННОГО ТИЕТАН-1,1-ДИОКСИДАЦель: исследовать диапазон эффективных доз нового производного 3-замещенного тиетан-
1,1-диоксида
Klen, E.E.,
Makarova, N.N.,
Khaliullin, F.A.,
Shepilova, S.O.,
Ishkinina, A.R.,
Baikova, I.P. (2022) (nitro)- and 3,5-dibromo-4-bromo(nitro)-
1-(
thietan-3-yl)-
1H-pyrazoles as convenient intermediate products
dimethyl 2-bromo-
1-(
thietan-3-yl)-
1H-imidazole-4,5-dicarboxylate which was oxidized to dimethyl 2-bromo-
1-(1