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11-PHENYLUNDECA-5Z,9Z-DIENOIC ACID: STEREOSELECTIVE SYNTHESIS AND DUAL TOPOISOMERASE I/IIΑ INHIBITION

Дьяконов, В.А., Джемилева, Л.У., Макаров, А.А., Мулюкова, А.Р., Хуснутдинова, Э.К., Джемилев, У.М., Толстикова Т. Г., Baev, D.S., D`yakonov, V.A., Dzhemileva, L.U., Makarov, A.A., Mulyukova, A.R., Khusnutdinova, E.K., Dzhemilev, U.M., Tolstikova, Tatiana G. (2015)

inhibitory activity of the synthesized acid with respect to human topoisomerase I (hTop1) and II (hTop2α

NOVEL HYBRID MOLECULES ON THE BASIS OF STEROIDS AND (5Z,9Z)-TETRADECA-5,9-DIENOIC ACID: SYNTHESIS, ANTI-CANCER STUDIES AND HUMAN TOPOISOMERASE I INHIBITORY ACTIVITY

D’yakonov, V.A., Dzhemileva, L.U., Tuktarova, R.A., Ishmukhametova, S.R., Yunusbaeva, M.M., Ramazanov, I.R., Dzhemilev, U.M. (2017)

, Jurkat, K562 cancer cell lines and human topoisomerase I (hTop1) inhibitory activity in vitro were found

ADVANCES IN THE CHEMISTRY OF NATURAL AND SEMISYNTHETIC TOPOISOMERASE I/II INHIBITORS

Дьяконов, В.А., Джемилева, Л.У., Джемилев, У.М., D'yakonov, V.A., Dzhemileva, L.U., Dzhemilev, U.M. (2017)

studies in this field have shown that topoisomerases I and II are one of the main molecular targets

SYNTHESIS AND TRANSFORMATIONS OF METALLACYCLES. 45. CROSS-CYCLOMAGNESIATION OF 1,2-DIENES IN THE SYNTHESIS OF 5Z, 9Z-DIENOIC ACIDS, EFFICIENT INHIBITORS OF HUMAN TOPOISOMERASE I

D’yakonov, V.A., Dzhemileva, L.U., Makarov, A.A., Mulyukova, A.R., Tuktarova, R.A., Islamov, I.I., Dzhemileva, U.M. (2015)

exhibited in vitro high inhibiting activity against human topoisomerase I.

CATALYTIC CYCLOMETALLATION IN STEROID CHEMISTRY III1 : SYNTHESIS OF STEROIDAL DERIVATIVES OF 5Z,9Z-DIENOIC ACID AND INVESTIGATION OF ITS HUMAN TOPOISOMERASE I INHIBITORY ACTIVITY

D’yakonov, V.A., Dzhemileva, L.U., Tuktarova, R.A., Makarov, A.A., Islamov, I.I., Mulyukova, A.R., Dzhemilev, U.M. (2015)

step. High inhibitory activity of the synthesized acids against human topoisomerase I (hTop1) was found.

NZ,(N + 4)Z-DIENOIC FATTY ACIDS: A NEW METHOD FOR THE SYNTHESIS AND INHIBITORY ACTION ON TOPOISOMERASE I AND IIA

D’yakonov, Vladimir A., Dzhemileva, Lilya U., Makarov, Aleksey A., Mulyukova, Alfiya R., Baev, Dmitry S, Khusnutdinova, Elza K, Tolstikova, Tatiana G., Dzhemilev, Usein M. (2016)

topoisomerase I and II was studied. Resorting to the data of molecular docking, a probable mechanism

NZ,(N + 4)Z-DIENOIC FATTY ACIDS: A NEW METHOD FOR THE SYNTHESIS AND INHIBITORY ACTION ON TOPOISOMERASE I AND IIA

D’yakonov, Vladimir A., Dzhemileva, Lilya U., Makarov, Aleksey A., Mulyukova, Alfiya R., Baev, Dmitry S., Khusnutdinova, Elza K., Tolstikova, Tatiana G., Dzhemilev, Usein M. (2016)

topoisomerase I and II was studied. Resorting to the data of molecular docking, a probable mechanism

CATALYTIC CYCLOMETALLATION IN STEROID CHEMISTRY III1: SYNTHESIS OF STEROIDAL DERIVATIVES OF 5Z,9Z-DIENOIC ACID AND INVESTIGATION OF ITS HUMAN TOPOISOMERASE I INHIBITORY ACTIVITY

Дьяконов, В.А., Джемилева, Л.У., Туктарова, Р.А., Макаров, А.А., Исламов, И.И., Мулюкова, А.Р., Джемилев, У.М., D’yakonov, Vladimir A., Dzhemileva, Lilya U., Tuktarova, Regina A., Makarov, Aleksey A., Islamov, Ilgiz I., Mulyukova, Alfiya R., Dzhemilev, Usein M. (2015)

step. High inhibitory activity of the synthesized acids against human topoisomerase I (hTop1) was found.

SHORT ROUTE TO THE TOTAL SYNTHESIS OF NATURAL MURICADIENIN AND INVESTIGATION OF ITS CYTOTOXIC PROPERTIES

Dzhemilev, Usein M., D’yakonov, Vladimir A., Tuktarova, Regina A., Dzhemileva, Lilya U., Ishmukhametova, Svetlana R., Yunusbaeva, Milyausha M., Armin de Meijere (2016)

activity against topoisomerases I and IIα, key cell cycle enzymes. Using flow cytometry, muricadienin

STEREOSELECTIVE SYNTHESIS OF 11-PHENYLUNDECA-5Z,9Z-DIENOIC ACID AND INVESTIGATION OF ITS HUMAN TOPOISOMERASE I AND IIA INHIBITORY ACTIVITY

Дьяконов, В.А., Джемилева, Л.У., Макаров, А.А., Мулюкова, А.Р., Хуснутдинова, Э.К., Джемилев, У.М., Baev, Dmitry S., Tolstikova, Tatiana G., D’yakonov, Vladimir A., Dzhemileva, Lilya U., Makarov, Aleksey A., Mulukova, Alfiya R., Khusnutdinova, Elza K., Dzhemilev, Usein M. (2015)

inhibitory activity of the synthesized acid with respect to human topoisomerase I (hTop1) and II (hTop2a

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