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studies in this field have shown that topoisomerases I and II are one of the main molecular targets

exhibited in vitro high inhibiting activity against human topoisomerase I.

, Jurkat, K562 cancer cell lines and human topoisomerase I (hTop1) inhibitory activity in vitro were found

CATALYTIC CYCLOMETALLATION IN STEROID CHEMISTRY III1 : SYNTHESIS OF STEROIDAL DERIVATIVES OF 5Z,9Z-DIENOIC ACID AND INVESTIGATION OF ITS HUMAN TOPOISOMERASE I INHIBITORY ACTIVITY step. High inhibitory activity of the synthesized acids against human topoisomerase I (hTop1) was found.

topoisomerase I and II was studied. Resorting to the data of molecular docking, a probable mechanism

topoisomerase I and II was studied. Resorting to the data of molecular docking, a probable mechanism

step. High inhibitory activity of the synthesized acids against human topoisomerase I (hTop1) was found.

inhibitory activity of the synthesized acid with respect to human topoisomerase I (hTop1) and II (hTop2α

inhibitory activity of the synthesized acid with respect to human topoisomerase I (hTop1) and II (hTop2a

on the activity of hydrolytic enzymes (amylases and proteinases) and their protein inhibitors in the leaves

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