Background: To examine fundamental characteristics of clinical
trials with therapeutic drug
Chu, Shuk Han,
Zhao, Xu,
Komber, Ahmad,
Cheyne, Joshua,
Wu, Simiao,
Cowey, Eileen,
Kutlubaev, Mansur,
Mead, Gillian (2023) reviews of randomized controlled
trials found insufficient evidence to guide practice, but most excluded
LEGG, L.A.,
TILNEY, R.,
HSIEH, C.F.,
WU, S.,
LUNDSTRÖM, E.,
RUDBERG, A.S.,
KUTLUBAEV, M.A.,
DENNIS, M.,
MEAD, G.E.,
SOLEIMANI, B.,
BARUGH, A.,
HACKETT, M.L.,
HANKEY, G.J (2019) in people who were not depressed at randomisation. A large
trial of fluoxetine for stroke recovery
Surgery in Metastatic Seminoma: Negative
Trial Should Be Treated as Negative
Wu, S.,
Kutlubaev, M.A.,
Chun, Ho-Yan Y,
Cowey, E.,
Pollock, A.,
Macleod, M.R.,
Dennis, M.,
Keane, E.,
Sharpe, M.,
Mead, G.E (2015) We retrieved 12,490 citations, obtained full texts for 58 studies and included 12
trials (three
MEAD, G.E.,
LEGG, L.,
TILNEY, R.,
HSIEH, C.F.,
WU, S.,
LUNDSTRÖM, E.,
RUDBERG, A.S.,
KUTLUBAEV, M.,
DENNIS, M.S.,
SOLEIMANI, B.,
BARUGH, A.,
HACKETT, M.L.,
HANKEY, G.J. (2020) included databases,
trials registers, reference lists, and contact with experts. Co-primary outcomes were
Agaverdiev, Murad,
Shamsov, Bedil,
Mirzoev, Sorbon,
Vardikyan, Andranik,
Encarnacion, Manuel Ramirez,
Nurmukhametov, Renat,
Beilerli, Aferin,
Zhang, Bohan,
Gareev, Ilgiz,
Pavlov, Valentin (2023) into two stages.
Results: By August 2022, there were 149 registered clinical
trials. Most studies belong
Han, Dayong,
Teng, Lei,
Wang, Xiaoxiong,
Zhen, Yunbo,
Chen, Xiaofeng,
Yang, Mingchun,
Gao, Ming,
Yang, Guang,
Han, Mingyang,
Wang, Ligang,
Xu, Jiajun,
Li, Yue,
Shumadalova, Alina,
Zhao, Shiguang (2022) , and the dose recommended for a phase II
trial is 1.5 mg. Copyright © 2022 Han, Teng, Wang, Zhen, Chen, Yang