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mode of miRNAs/target genes regulation in the development and progression of IA and TAA/AAA. The aim

endogenous non-coding RNAs orchestrating post-transcriptional gene expression, have garnered substantial

led to a significant advancement in gene expression analysis platforms. Microarray analysis has gained

are mainly limited to determining the role of protein-coding genes, near or within which these polymorphisms

. Methods: We utilized a custom next-generation sequencing (NGS) panel targeting 48 genes implicated

in the field of the early diagnosis and targeted therapy of the disease. The Runt-related transcription factor

regulator gene (CFTR) mutations in the population, which is determined by genetic diversity and ethnicity

., through gene repression. A growing number of studies have demonstrated miRNAs deregulation in various

Ретроэлементы как мишени таргетной терапии опухолей (обзор) in targeted antitumor therapy (review). Research Results in Biomedicine. 2024; 10(1): 5-22. Russian]. DOI: 10

a combination of prototype M1 and M2 genes. Our review focuses on novel mechanisms involved

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