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was to analyze the association of polymorphic variants of the methylenetetrahydrofolate reductase MTHFR (rs

are mainly limited to determining the role of protein-coding genes, near or within which these polymorphisms

variants were determined using a real-time polymerase chain reaction. The polymorphic variant rs16944

reactions. The aim of the research was to study the role of polymorphic variants of the AOC1, HRH2, HRH3

Исследование роли полиморфных вариантов генов MTHFR и MTRR в развитии желчнокаменной болезниThe role of MTHFR and MTRR gene polymorphisms in the development of cholelithiasis

discovered, along with the polymorphic variant rs1042522 in the TP53 gene, which has been associated

with microRNAs. Methods: The authors searched for associations of polymorphic variants of microRNA binding

is to identify the association between polymorphic variants of H19 (rs3741219), MEG3 (rs7158663), MALAT1 (rs

studied polymorphic variants of candidate genes (ACAN, ADAMTS5, CHST11, SOX9, COL1A1) for OA development

610 000 single nucleotide polymorphic variants (SNPs). The studied sample consisted of 357 patients

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