PT - JOURNAL ARTICLE
AU - , 
AU - , 
AU - , 
AU - , 
TI - 
DP - 2020-10-27
4100 - 10.1002/eji.201970300
SO - https://repo.bashgmu.ru/publication/923
AB - TAMs (tumor-associated macrophages) are innate immune cells, which are present in prostate cancer (PC) tissue.
TAMs play major role in tumor progression, invasion, neoangiogenesis, metastasis and resistance to therapy. Prostate
cancer patients often have long time periods between curative intent surgery or radiation therapy until the time of
biochemical recurrence or metastatic relapse is detectable but the disease at this stage can be incurable with the
current treatment options. We believe that correctly identifying the phenotype of TAMs and the corresponding
molecular biomarkers can predict the aggressiveness of PC, response to chemotherapy and development of
postoperative metastasis.