17 2019 2020-10-27 10.1002/eji.201970300 TAMs (tumor-associated macrophages) are innate immune cells, which are present in prostate cancer (PC) tissue. TAMs play major role in tumor progression, invasion, neoangiogenesis, metastasis and resistance to therapy. Prostate cancer patients often have long time periods between curative intent surgery or radiation therapy until the time of biochemical recurrence or metastatic relapse is detectable but the disease at this stage can be incurable with the current treatment options. We believe that correctly identifying the phenotype of TAMs and the corresponding molecular biomarkers can predict the aggressiveness of PC, response to chemotherapy and development of postoperative metastasis. https://repo.bashgmu.ru/publication/923 https://repo.bashgmu.ru/files/1047