SYNTHESIS AND ANTIDEPRESSANT PROPERTIES OF 3-METHYL-7-(1,1-DIOXOTHIETAN-3-YL)-8-CYCLOHEXYLAMINO-1-ETHYL-1H-PURINE-2,6(3H,7H)-DIONE

Khaliullin, F.A. Shabalina, Y.V. Davlyatova, G.G. Valeeva, L.A. SYNTHESIS AND ANTIDEPRESSANT PROPERTIES OF 3-METHYL-7-(1,1-DIOXOTHIETAN-3-YL)-8-CYCLOHEXYLAMINO-1-ETHYL-1H-PURINE-2,6(3H,7H)-DIONE 2018

2018-07-05

3-Methyl-7-(1,1-dioxothietan-3-yl)-8-cyclohexylamino-1-ethyl-1H-purine-2,6(3H,7H)-dione was synthesized via the reaction of 8-bromo-3-methyl-7-(1,1-dioxothietan-3-yl)-1-ethyl-1H-purine-2,6(3H,7H)-dione and cyclohexylamine and exhibited antidepressant activity that was most pronounced at a dose of 1.6 mg/kg. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.

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