TY - JOUR T1 - AU - Raskildinaa, G.Z., AU - Valieva, V.F., AU - Ozdena, I.V., AU - Meshcheryakova, S.A., AU - Spirikhin, L.V., AU - Zlotskiia, S.S., Y1 - 2018-03-07 UR - https://repo.bashgmu.ru/publication/697 N2 - 6-Methyluracil derivatives containing a gem-dichlorocyclopropane and a 1,3-dioxolane fragments were synthesized for the first time. The condensation of 6-methyluracil with chloromethyl derivatives gives a mixture of N1 - and N3 -monosubstituted products, and the profound N-alkylation of this compound provides disubstituted uracils. The structure of the synthesized compounds was studied by H1 and 13ะก NMR spectroscopy and their relative antioxidant activity was evaluated by luminol-dependent chemiluminescence measurements.