RT - Article SR - Electronic T1 - SP - 2018-03-07 A1 - Raskildinaa, G.Z., A1 - Valieva, V.F., A1 - Ozdena, I.V., A1 - Meshcheryakova, S.A., A1 - Spirikhin, L.V., A1 - Zlotskiia, S.S., YR - 2017 UL - https://repo.bashgmu.ru/publication/697 AB - 6-Methyluracil derivatives containing a gem-dichlorocyclopropane and a 1,3-dioxolane fragments were synthesized for the first time. The condensation of 6-methyluracil with chloromethyl derivatives gives a mixture of N1 - and N3 -monosubstituted products, and the profound N-alkylation of this compound provides disubstituted uracils. The structure of the synthesized compounds was studied by H1 and 13ะก NMR spectroscopy and their relative antioxidant activity was evaluated by luminol-dependent chemiluminescence measurements.