Karimova, E.R. Baltina, L.A. Spirikhin, L.V. Kondratenko, R.M. Farkhutdinov, R.R. Petrova, I.V. 2015

2018-02-27

Quercetin (Q) methyl ethers were synthesized from CH3I under various conditions. The principal products from the reactions of Q with alkylhalides (CH3I, C4H9Br) in DMF were 3,7,4′-tri-O-alkyl ethers. The structures of the products were confirmed by PMR and 13C NMR spectra. The antioxidant activity of Q tetra- and tri-O-methyl ethers was demonstrated by chemiluminescence in model systems generating active oxygen species and promoting lipid peroxidation.

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