PT - JOURNAL ARTICLE
AU - Suberville, M., 
AU - Zhang, K., 
AU - Woillard, J.B., 
AU - Herafa, I., 
AU - Ducoux, D., 
AU - Nachef, R., 
AU - Teoh, J., 
AU - Zhu, G., 
AU - Chi-Fai Ng, 
AU - Laguna, P., 
AU - Jean de la Rosette, 
TI - Oncological and Functional Outcomes of Hemi-Ablation Versus Focal Ablation for Localized Prostate Cancer Using Irreversible Electroporation
DP - 2026-05-21
TA - CANCERS
4100 - 10.3390/cancers17132084
SO - https://repo.bashgmu.ru/publication/5382
AB - For localized prostate cancer, focal therapy uses different sources of energy to treat selected
areas of the gland, thereby avoiding or limiting damage to surrounding structures and
aiming to preserve urinary and erectile function. Irreversible electroporation (IRE) is a
novel tumor ablation technique using a non-thermal energy source, which might have
potential advantages over other focal therapy modalities and achieve superior functional
and safety outcomes. The aim of our retrospective study was to assess the oncological
control, functional outcomes, and quality-of-life results of hemi-IRE ablation versus focal
IRE ablation therapy for localized prostate cancer patients in a short- to medium-term
follow-up. We confirmed that both IRE protocols achieved good urinary and erectile
function outcomes and favorable short-term oncological control and that hemi-IRE ablation
showed a significantly lower persistence of (clinically significant) prostate cancer compared
with focal IRE ablation.