17 Suberville, M. Zhang, K. Woillard, J.B. Herafa, I. Ducoux, D. Nachef, R. Teoh, J. Zhu, G. Chi-Fai Ng Laguna, P. Jean de la Rosette irreversible electroporation side effect patient-reported quality of life prostate cancer focal therapy Scopus Web of Science Белый список 2025 2026-05-21 10.3390/cancers17132084 CANCERS For localized prostate cancer, focal therapy uses different sources of energy to treat selected areas of the gland, thereby avoiding or limiting damage to surrounding structures and aiming to preserve urinary and erectile function. Irreversible electroporation (IRE) is a novel tumor ablation technique using a non-thermal energy source, which might have potential advantages over other focal therapy modalities and achieve superior functional and safety outcomes. The aim of our retrospective study was to assess the oncological control, functional outcomes, and quality-of-life results of hemi-IRE ablation versus focal IRE ablation therapy for localized prostate cancer patients in a short- to medium-term follow-up. We confirmed that both IRE protocols achieved good urinary and erectile function outcomes and favorable short-term oncological control and that hemi-IRE ablation showed a significantly lower persistence of (clinically significant) prostate cancer compared with focal IRE ablation. https://repo.bashgmu.ru/publication/5382 https://repo.bashgmu.ru/files/5576