PT - JOURNAL ARTICLE
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DP - 2024-12-09
4100 - 10.1134/S1070363224080085
SO - https://repo.bashgmu.ru/publication/4755
AB - New phosphorus-containing isatin-3-hydrazones were synthesized by the condensation reaction of 5-substituted isatins with 2-chloroethyl [4-(dimethylamino)phenyl](2-hydrazinyl-2-oxoethyl)phosphinate (KAPAKh). The resulting compounds were shown to have high antitumor activity against duodenal adenocarcinoma (HuTu80) and cervical epithelioid carcinoma (M-HeLa) cell lines with low toxicity towards erythrocytes and normal human liver cells. © Pleiades Publishing, Ltd. 2024.