17 2020 2021-03-10 10.2478/sjecr-2020-0033 Introduction. In endosurgery of the digestive tract, ‘cellular technologies’ are gaining popularity, including the use of blood components or blood cells with a haemostatic purpose. In this re gard, the objective of the study is evaluation of the effectiveness of bleeding control and safety of resection of the hollow organs of the digestive tract in the experimental trauma models of the ab dominal organs in laboratory animals. Materials and methods. The study was conducted in 20 mature male Chinchilla rabbits with the mean body mass of 2450 ± 210 g. All animals were di vided into four experimental groups: the control group (without bleeding control); the group that received the infiltration of the wall of a hollow organ with saline; the group in which bleeding was controlled by argon plasma coagulation (APC), and the group wherein animals underwent haemostasis with autoplasma. Results . In the control group and the physiological saline group, no statistical difference was observed in the time of bleeding con trol. Autoplasma, due to preventive local administration, is more effective than APC and has a high haemostatic potential. Conclu sion . Autoplasma has been found to be highly effective and safe for bleeding control in the gastrointestinal tract in the experi mental model, which has paved the way for new possibilities for operations of various scales, including endoscopic operations. https://repo.bashgmu.ru/publication/4641 https://repo.bashgmu.ru/files/4817