17 2022 2022-10-10 10.35630/2199-885X/2022/12/1.24 This article presents the study of a dental gel developed by us, containing, as an active ingredient, sanguitrithrin and oil extract from calendula flowers and yarrow grass. As a result of our studies of the dental gel on 1,844 children and adolescents, we revealed that it has antiinflammatory and wound-healing activities and produces anti-inflammatory, reparative, hemostatic and trophic effects. The results of the study make it possible to use the dental gel in clinical practice for treatment of inflammatory periodontal diseases in children. We substantiated the prospects of using the phytocomplex in the form of a dental gel and proved it as effective and safe. Besides, its dosage form is convenient for use in dental practice and even provides advantages over known domestic analogues. https://repo.bashgmu.ru/publication/3757 https://repo.bashgmu.ru/files/3933