@article{2021-12-14, author = {, , , , , , , , , }, title = {}, year = {2021}, doi = {10.1007/s11094-021-02491-0}, publisher = {NP «NEICON»}, abstract = {The development and optimization of synthetic methods for alkyl esters of 4-[(1H-azol-1-yl)methyl]phenols enabled the expansion of organic synthesis methodology, which is extremely important for designing new structures with various types of biological activity, e.g., antiaggregant and anticoagulant. The present work studied O-alkylation of 4-[(1H-azol-1-yl)methyl]phenols with various alkylating agents, e.g., n-octyl bromide, n-hexadecyl bromide, and (adamantyl-1)bromomethylketone. The newly synthesized compounds were identified using elemental analysis and IR and PMR spectroscopy. Laboratory studies of blood isolated from healthy volunteers revealed compounds with antiaggregant and anticoagulant properties.}, URL = {https://repo.bashgmu.ru/publication/2058}, eprint = {https://repo.bashgmu.ru/files/2230}, }