RT - Article
SR - Electronic
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SP - 2021-01-25
DO - 10.1016/j.surfcoat.2020.126486
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YR - 2020
UL - https://repo.bashgmu.ru/publication/1419
AB - The paper concerns a choice in the biofunctionalization of the coatings produced by plasma electrolytic oxidation: either with inorganic components by introducing Ca-, P- containing compounds into the coating (primarily hydroxyapatite), or with integrin-active organic components (primarily RGD peptides). The following coatings were analyzed: E1 - titania PEO coating, E2 - titania and Ca-, P containing PEO coating, E1- RGD titania PEO coating modified with integrin-active RGD (arginine-glycine-aspartic acid) tripeptide sequence anchored to the surface with a bisphosphonate linker. In terms of wear resistance, electrochemical corrosion behavior, and interaction with osteoblast-like cells, coating E1 + RGD seems to be the most promising for the titanium implants.