@article{2021-08-05, author = {, , , , , , , , }, title = {}, year = {2021}, doi = {10.1007/s11094-021-02424-x}, publisher = {NP «NEICON»}, abstract = {The hypoglycemic activity of glycyrrhizic acid (GA, I), its trisodium (II) and sodium-dilithium salts (III), and a conjugate with L-methionine methyl ester (IV) was studied using an alloxan diabetes model after peroral administration to male Wistar rats. It was found that GA and its conjugate IV at a dose of 100 mg/kg exhibited hypoglycemic activity and reduced the blood glucose content of the animals by 35.5 and 42.6%, respectively, after 120 min. GA conjugate IV had low toxicity and hypoglycemic activity superior to those of GA and acarbose.}, URL = {https://repo.bashgmu.ru/publication/1327}, eprint = {https://repo.bashgmu.ru/files/1497}, }