TY  - JOUR
T1  - СИНТЕЗ ПРОИЗВОДНЫХ ПИРИМИДИН-2,4(Ш,3Щ-ДИОНОВ, СОДЕРЖАЩИХ N-АЛКИЛЬНЫЕ ЗАМЕСТИТЕЛИ
DO  - 10.1134/S1070363217080369
AU  - , 
AU  - , 
AU  - , 
AU  - , 
AU  - , 
AU  - , 
AU  - Раскильдина Г.З.,, 
AU  - Валиев В.Ф.,, 
AU  - Озден И.В.,, 
AU  - Мещерякова С.А.,, 
AU  - Спирихин Л.В.,, 
AU  - Злотский С.С., 
Y1  - 2020-12-17
UR  - https://repo.bashgmu.ru/publication/1267
N2  - 6-Methyluracil derivatives containing a gem-dichlorocyclopropane and a 1,3-dioxolane fragments were synthesized for the first time. The condensation of 6-methyluracil with chloromethyl derivatives gives a mixture of N1- and N3-monosubstituted products, and the profound N-alkylation of this compound provides disubstituted uracils. The structure of the synthesized compounds was studied by H1 and 13С NMR spectroscopy and their relative antioxidant activity was evaluated by luminol-dependent chemiluminescence measurements.