%0 Article
%A , 
%A , 
%A , 
%A , 
%A , 
%A , 
%A Раскильдина Г.З.,, 
%A Валиев В.Ф.,, 
%A Озден И.В.,, 
%A Мещерякова С.А.,, 
%A Спирихин Л.В.,, 
%A Злотский С.С., 
%T СИНТЕЗ ПРОИЗВОДНЫХ ПИРИМИДИН-2,4(Ш,3Щ-ДИОНОВ, СОДЕРЖАЩИХ N-АЛКИЛЬНЫЕ ЗАМЕСТИТЕЛИ
%D 2017
%R 10.1134/S1070363217080369
%X 6-Methyluracil derivatives containing a gem-dichlorocyclopropane and a 1,3-dioxolane fragments were synthesized for the first time. The condensation of 6-methyluracil with chloromethyl derivatives gives a mixture of N1- and N3-monosubstituted products, and the profound N-alkylation of this compound provides disubstituted uracils. The structure of the synthesized compounds was studied by H1 and 13С NMR spectroscopy and their relative antioxidant activity was evaluated by luminol-dependent chemiluminescence measurements.
%U https://repo.bashgmu.ru/publication/1267