RT - Article
SR - Electronic
T1 - 
SP - 2018-03-07
DO - 10.1007/s11094-017-1649-5
A1 - Spasov, A.A., 
A1 - Khaliullin, F.A., 
A1 - Babkov, D.A., 
A1 - Timirkhanova, G.A., 
A1 - Kuznetsova, V.A., 
A1 - Naumenko, L.V., 
A1 - Muleeva, D.R., 
A1 - Maika, O.Yu., 
A1 - Prokhorova, T.Yu., 
A1 - Sturova, E.A., 
YR - 2017
UL - https://repo.bashgmu.ru/publication/1126
AB - Thiazolo[2, 3-f]purine derivatives and their analogs – dihydrothiazolo[2, 3-f]purine, 7-(thietan-3-yl)purine,
and 8-(2-hydroxypropylthio)purine derivatives – were synthesized. The compounds synthesized here had no
effects on protein glycation reactions using glucose; they gave weak inhibition of glycogen phosphorylase;
they had no hemorheological activity. Substances with hypotensive activity greater than that of Dibazol were
found. A number of substances had hypoglycemic effects greater than those of chlorpropamide and Adebit.
Two compounds inhibited dipeptidylpeptidase-4, but were less active than reference agent vildagliptin.