17 Spasov, A.A. Khaliullin, F.A. Babkov, D.A. Timirkhanova, G.A. Kuznetsova, V.A. Naumenko, L.V. Muleeva, D.R. Maika, O.Yu. Prokhorova, T.Yu. Sturova, E.A. 2017 2018-03-07 10.1007/s11094-017-1649-5 Thiazolo[2, 3-f]purine derivatives and their analogs – dihydrothiazolo[2, 3-f]purine, 7-(thietan-3-yl)purine, and 8-(2-hydroxypropylthio)purine derivatives – were synthesized. The compounds synthesized here had no effects on protein glycation reactions using glucose; they gave weak inhibition of glycogen phosphorylase; they had no hemorheological activity. Substances with hypotensive activity greater than that of Dibazol were found. A number of substances had hypoglycemic effects greater than those of chlorpropamide and Adebit. Two compounds inhibited dipeptidylpeptidase-4, but were less active than reference agent vildagliptin. https://repo.bashgmu.ru/publication/1126 https://repo.bashgmu.ru/files/1283