%0 Article
%A Spasov, A.A., 
%A Khaliullin, F.A., 
%A Babkov, D.A., 
%A Timirkhanova, G.A., 
%A Kuznetsova, V.A., 
%A Naumenko, L.V., 
%A Muleeva, D.R., 
%A Maika, O.Yu., 
%A Prokhorova, T.Yu., 
%A Sturova, E.A., 
%T 
%D 2017
%R 10.1007/s11094-017-1649-5
%X Thiazolo[2, 3-f]purine derivatives and their analogs – dihydrothiazolo[2, 3-f]purine, 7-(thietan-3-yl)purine,
and 8-(2-hydroxypropylthio)purine derivatives – were synthesized. The compounds synthesized here had no
effects on protein glycation reactions using glucose; they gave weak inhibition of glycogen phosphorylase;
they had no hemorheological activity. Substances with hypotensive activity greater than that of Dibazol were
found. A number of substances had hypoglycemic effects greater than those of chlorpropamide and Adebit.
Two compounds inhibited dipeptidylpeptidase-4, but were less active than reference agent vildagliptin.
%U https://repo.bashgmu.ru/publication/1126