@article{Spasov, A.A.2018-03-07, author = { Spasov, A.A., Khaliullin, F.A., Babkov, D.A., Timirkhanova, G.A., Kuznetsova, V.A., Naumenko, L.V., Muleeva, D.R., Maika, O.Yu., Prokhorova, T.Yu., Sturova, E.A.}, title = {}, year = {2017}, doi = {10.1007/s11094-017-1649-5}, publisher = {NP «NEICON»}, abstract = {Thiazolo[2, 3-f]purine derivatives and their analogs – dihydrothiazolo[2, 3-f]purine, 7-(thietan-3-yl)purine, and 8-(2-hydroxypropylthio)purine derivatives – were synthesized. The compounds synthesized here had no effects on protein glycation reactions using glucose; they gave weak inhibition of glycogen phosphorylase; they had no hemorheological activity. Substances with hypotensive activity greater than that of Dibazol were found. A number of substances had hypoglycemic effects greater than those of chlorpropamide and Adebit. Two compounds inhibited dipeptidylpeptidase-4, but were less active than reference agent vildagliptin.}, URL = {https://repo.bashgmu.ru/publication/1126}, eprint = {https://repo.bashgmu.ru/files/1283}, }