@article{2020-09-16, author = {, , , , , }, title = {}, year = {2020}, doi = {10.1007/s11094-020-02184-0}, publisher = {NP «NEICON»}, abstract = {A conjugate of glycyrrhizic acid (GA) with L-phenylalanine methyl ester was synthesized using N-hydroxysuccinimide and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide. Chemical modification of GA via addition of L-phenylalanine methyl ester moieties in the carbohydrate part of the glycoside was shown to form a marginally toxic compound with high anti-inflammatory activity in carrageenan- and formalin-induced mouse inflammation models and with pronounced antiulcer activity in rats. This was a significant advantage of this compound over known anti-inflammatory drugs.}, URL = {https://repo.bashgmu.ru/publication/1041}, eprint = {https://repo.bashgmu.ru/files/1190}, }