TY  - JOUR
T1  - Компьютерный анализ взаимосвязи структура – ​​активность для иммуноактивных производных тиазоло [3,2- a ] бензимидазола
DO  - 10.1007/s11094-018-1814-5
AU  - Дианов, В.М., 
AU  - Алехин, Е.К., 
AU  - Тюрина, Л.А., 
Y1  - 2020-12-14
UR  - https://repo.bashgmu.ru/publication/1037
N2  - Computer analysis of the structure–activity relationship and purposeful design of effective immunomodulators among thiazolo[3,2-a]benzimidazole derivatives was performed. A mathematical recognition model was formulated. Immunomodulating activity of condensed azoles was predicted (80 – 100% learning recognition). Potentially active structures were generated. Their activities were predicted. Theoretical and experimental results agreed. The tested thiazolo[3,2-a]benzimidazole derivatives exhibited the predicted activities. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.