RT - Article
SR - Electronic
T1 - Компьютерный анализ взаимосвязи структура – ​​активность для иммуноактивных производных тиазоло [3,2- a ] бензимидазола
SP - 2020-12-14
DO - 10.1007/s11094-018-1814-5
A1 - Дианов, В.М., 
A1 - Алехин, Е.К., 
A1 - Тюрина, Л.А., 
YR - 2018
UL - https://repo.bashgmu.ru/publication/1037
AB - Computer analysis of the structure–activity relationship and purposeful design of effective immunomodulators among thiazolo[3,2-a]benzimidazole derivatives was performed. A mathematical recognition model was formulated. Immunomodulating activity of condensed azoles was predicted (80 – 100% learning recognition). Potentially active structures were generated. Their activities were predicted. Theoretical and experimental results agreed. The tested thiazolo[3,2-a]benzimidazole derivatives exhibited the predicted activities. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.