HUMAN INDUCED PLURIPOTENT STEM CELL LINE HMUI001-A DERIVED FROM CORNEAL STROMAL CELLS

Publication date: 2019

DOI: 10.1016/j.scr.2019.101409

Abstract:

A human corneal stroma induced pluripotent stem cell (HMUi001-A) line was created from primary cultured human corneal fibroblasts. Reprogramming was performed using episomal vector delivery of OCT4, SOX2, KLF4, L-MYC and LIN28. Further characterization of the HMUi001-A confirmed that the cell line was pluripotent, free from Epstein Barr viral genome, and retained normal karyotype.

Тип: Article